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National Executive Committee
COVID-19 Research Projects
Section 56 Consultation
Follow-Up Study of Federal Inmates on Opioid Agonist Treatment in Ontario
Implementation Science Program
Detoxification and Withdrawal Management
COVID-19 Rapid Guidance
Opioid Use Disorder
Lower Risk Cannabis Use Guidelines
Best Practice Document on Harm Reduction Programs for PWUD
Chronic Disease Self-management Experiences among Marginalized PWUD
Impacts of Overdose Study
It Takes a Village
Best Practices in Buprenorphine/Naloxone Initiation in Provincial Correctional Facilities
Asset Mapping of Substance Use Prevention and Intervention Programs and Services
Surviving Opioid Overdose with Naloxone Education and Resuscitation
Integrating Access to Anti-Craving Medications for Adult Women with SUD
Northern Ontario Drug Use and Service Needs Assessment (NODUS)
Youth Substance Use Service Provider Study
Identifying Service Needs among PWUD
Publications and Reports
Academic Journal Articles
Ontario Drug Use Compendium
Surviving Opioid Overdose with Naloxone Education and Resuscitation (SOONER)
PI and project team:
Rehm, J., Charters, D., & Strike, C.
The goal of this project is to design and evaluate a novel overdose education and naloxone distribution toolkit for clinical settings. The project has three phases. In phase one, a naloxone distribution and training toolkit for open-access distribution was co-designed in collaboration with St. Michael's Hospital and the Ontario College of Art and Design (OCAD) University. Phase two involved feasibility trials to establish recruitment and retention strategies for a full-scale RCT. During phase three (the RCT phase), people likely to witness overdose will be recruited in emergency department, family practice, and addictions medicine settings and randomized to either the novel naloxone training kit and tool, or existing community-based standard of care. The primary outcome will be satisfactory bystander first aid in a simulated opioid overdose scenario, conducted within two weeks of recruitment.
Successes and Opportunities:
The SOONER Feasibility study demonstrated project feasibility in addictions medicine, family practice, and ED settings. This shows that a simulation-based RCT is logistically feasible. The feasibility study is published in
and the associated protocol is published in
The SOONER Feasibility study also offers a replicable model for recruiting and retaining people who use drugs and who are likely to witness opioid overdose in a RCT. This is an independent innovation that can serve the research community and CRISM nationally and internationally.
Manuscripts concerning the SOONER simulation model, and the outcomes of the SOONER co-design research are complete and under peer review.
Although COVID-19 has generated many challenging disruptions for SOONER, the need for brief point-of-care naloxone distribution tools is more acute than before. Quite unexpectedly, COVID-19 has made the SOONER training tools more applicable than before. A number of community stakeholders are interested in implementing the tool in practice and we plan to pursue this implementation and KT opportunity.